De-novo design, synthesis and evaluation of novel 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline derivatives as HIV-1 reverse transcriptase inhibitors

BACKGROUND: Acquired Immune Deficiency Syndrome (AIDS) is the advanced stage of infection caused by Human Immunodeficiency Virus (HIV). HIV/AIDS had a great impact on society, both as an illness and as a source of discrimination. Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) are structura...

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Detalles Bibliográficos
Autores principales: Chander, Subhash, Ashok, Penta, Singh, Anupam, Murugesan, Sankaranarayanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463983/
https://www.ncbi.nlm.nih.gov/pubmed/26075019
http://dx.doi.org/10.1186/s13065-015-0111-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4463983/
https://www.ncbi.nlm.nih.gov/pubmed/26075019
http://dx.doi.org/10.1186/s13065-015-0111-6

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