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PPAR-Alpha Agonist Used at the Acute Phase of Experimental Ischemic Stroke Reduces Occurrence of Thrombolysis-Induced Hemorrhage in Rats

The impact of fenofibrate, a peroxisome proliferator-activated receptor-alpha (PPAR-α) agonist, on the risk of thrombolysis-induced hemorrhage during the acute phase of stroke in a rat model of stroke was studied. One-hour middle cerebral artery occlusion followed by thrombolysis with tissue plasmin...

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Detalles Bibliográficos
Autores principales: Gautier, Sophie, Ouk, Thavarak, Pétrault, Maud, Pétrault, Olivier, Bérézowski, Vincent, Bordet, Régis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464007/
https://www.ncbi.nlm.nih.gov/pubmed/26106408
http://dx.doi.org/10.1155/2015/246329