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Mitogen-activated protein kinase mediates mevalonate-stimulated human mesangial cell proliferation

The metabolic products of intracellular mevalonate (MVA) are important for the growth of eukaryotic cells. These products include cholesterol and several non-sterol isoprenoids. It has been reported that 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors ameliorate glomerular injury in sever...

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Detalles Bibliográficos
Autores principales: ZHOU, XIAOSHUANG, WANG, CHEN, TIAN, JIHUA, WANG, YANHONG, LI, YAFENG, HU, ZHAOYONG, LI, RONGSHAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464046/
https://www.ncbi.nlm.nih.gov/pubmed/25936991
http://dx.doi.org/10.3892/mmr.2015.3715