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Preferential Amplification of Pathogenic Sequences

The application of next generation sequencing (NGS) technology in the diagnosis of human pathogens is hindered by the fact that pathogenic sequences, especially viral, are often scarce in human clinical specimens. This known disproportion leads to the requirement of subsequent deep sequencing and ex...

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Detalles Bibliográficos
Autores principales: Ge, Fang, Parker, Jayme, Chul Choi, Sang, Layer, Mark, Ross, Katherine, Jilly, Bernard, Chen, Jack
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464073/
https://www.ncbi.nlm.nih.gov/pubmed/26067233
http://dx.doi.org/10.1038/srep11047