The HRDC domain of E. coli RecQ helicase controls single-stranded DNA translocation and double-stranded DNA unwinding rates without affecting mechanoenzymatic coupling

DNA-restructuring activities of RecQ-family helicases play key roles in genome maintenance. These activities, driven by two tandem RecA-like core domains, are thought to be controlled by accessory DNA-binding elements including the helicase-and-RnaseD-C-terminal (HRDC) domain. The HRDC domain of hum...

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Detalles Bibliográficos
Autores principales: Harami, Gábor M., Nagy, Nikolett T., Martina, Máté, Neuman, Keir C., Kovács, Mihály
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464074/
https://www.ncbi.nlm.nih.gov/pubmed/26067769
http://dx.doi.org/10.1038/srep11091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464074/
https://www.ncbi.nlm.nih.gov/pubmed/26067769
http://dx.doi.org/10.1038/srep11091

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