Cargando…

The HRDC domain of E. coli RecQ helicase controls single-stranded DNA translocation and double-stranded DNA unwinding rates without affecting mechanoenzymatic coupling

DNA-restructuring activities of RecQ-family helicases play key roles in genome maintenance. These activities, driven by two tandem RecA-like core domains, are thought to be controlled by accessory DNA-binding elements including the helicase-and-RnaseD-C-terminal (HRDC) domain. The HRDC domain of hum...

Descripción completa

Detalles Bibliográficos
Autores principales:	Harami, Gábor M., Nagy, Nikolett T., Martina, Máté, Neuman, Keir C., Kovács, Mihály
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464074/ https://www.ncbi.nlm.nih.gov/pubmed/26067769 http://dx.doi.org/10.1038/srep11091

Ejemplares similares

RecQ helicase triggers a binding mode change in the SSB–DNA complex to efficiently initiate DNA unwinding
por: Mills, Maria, et al.
Publicado: (2017)

Mechanism of RecQ helicase mechanoenzymatic coupling reveals that the DNA interactions of the ADP-bound enzyme control translocation run terminations
por: Sarlós, Kata, et al.
Publicado: (2015)

Homology sensing via non-linear amplification of sequence-dependent pausing by RecQ helicase
por: Seol, Yeonee, et al.
Publicado: (2019)

Human RecQ Helicases in DNA Double-Strand Break Repair
por: Lu, Huiming, et al.
Publicado: (2021)

Molecular characteristics of reiterative DNA unwinding by the Caenorhabditis elegans RecQ helicase
por: Choi, Seoyun, et al.
Publicado: (2019)

Processive translocation mechanism of the human Bloom’s syndrome helicase along single-stranded DNA
por: Gyimesi, Máté, et al.
Publicado: (2010)

Fork sensing and strand switching control antagonistic activities of RecQ helicases
por: Klaue, Daniel, et al.
Publicado: (2013)

Sit down, relax and unwind: structural insights into RecQ helicase mechanisms
por: Killoran, Michael P., et al.
Publicado: (2006)

RecQ helicases in DNA repair and cancer targets
por: Newman, Joseph A., et al.
Publicado: (2020)

A guanine-flipping and sequestration mechanism for G-quadruplex unwinding by RecQ helicases
por: Voter, Andrew F., et al.
Publicado: (2018)

Structure and function of the regulatory C-terminal HRDC domain from Deinococcus radiodurans RecQ
por: Killoran, Michael P., et al.
Publicado: (2008)

Human premature aging, DNA repair and RecQ helicases
por: Brosh, Robert M., et al.
Publicado: (2007)

Human RECQ5 helicase promotes repair of DNA double-strand breaks by synthesis-dependent strand annealing
por: Paliwal, Shreya, et al.
Publicado: (2014)

Non-B DNA Secondary Structures and Their Resolution by RecQ Helicases
por: Sharma, Sudha
Publicado: (2011)

Maintenance of Yeast Genome Integrity by RecQ Family DNA Helicases
por: Gupta, Sonia Vidushi, et al.
Publicado: (2020)

ATPase Cycle and DNA Unwinding Kinetics of RecG Helicase
por: Toseland, Christopher P., et al.
Publicado: (2012)

Mechanism of Werner DNA Helicase: POT1 and RPA Stimulates WRN to Unwind beyond Gaps in the Translocating Strand
por: Ahn, Byungchan, et al.
Publicado: (2009)

Switching from single-stranded to double-stranded DNA limits the unwinding processivity of ring-shaped T7 DNA helicase
por: Jeong, Yong-Joo, et al.
Publicado: (2013)

Rev7 and 53BP1/Crb2 prevent RecQ helicase-dependent hyper-resection of DNA double-strand breaks
por: Leland, Bryan A, et al.
Publicado: (2018)

Ring-shaped replicative helicase encircles double-stranded DNA during unwinding
por: Joo, Sihwa, et al.
Publicado: (2019)

RecQ Helicase Somatic Alterations in Cancer
por: Thakkar, Megha K., et al.
Publicado: (2022)

Simultaneous binding to the tracking strand, displaced strand and the duplex of a DNA fork enhances unwinding by Dda helicase
por: Aarattuthodiyil, Suja, et al.
Publicado: (2014)

Nanopore tweezers measurements of RecQ conformational changes reveal the energy landscape of helicase motion
por: Craig, Jonathan M, et al.
Publicado: (2022)

RecQ helicases: lessons from model organisms
por: Cobb, Jennifer A., et al.
Publicado: (2006)

DNA Unwinding by Ring-Shaped T4 Helicase gp41 Is Hindered by Tension on the Occluded Strand
por: Ribeck, Noah, et al.
Publicado: (2013)

Structural mechanisms of human RecQ helicases WRN and BLM
por: Kitano, Ken
Publicado: (2014)

Action of CMG with strand-specific DNA blocks supports an internal unwinding mode for the eukaryotic replicative helicase
por: Langston, Lance, et al.
Publicado: (2017)

The toposiomerase IIIalpha-RMI1-RMI2 complex orients human Bloom’s syndrome helicase for efficient disruption of D-loops
por: Harami, Gábor M., et al.
Publicado: (2022)

Mycobacterium smegmatis RqlH defines a novel clade of bacterial RecQ-like DNA helicases with ATP-dependent 3′–5′ translocase and duplex unwinding activities
por: Ordonez, Heather, et al.
Publicado: (2012)

Complex activities of the human Bloom's syndrome helicase are encoded in a core region comprising the RecA and Zn-binding domains
por: Gyimesi, Máté, et al.
Publicado: (2012)

The roles of WRN and BLM RecQ helicases in the Alternative Lengthening of Telomeres
por: Mendez-Bermudez, Aaron, et al.
Publicado: (2012)

The process of displacing the single-stranded DNA-binding protein from single-stranded DNA by RecO and RecR proteins
por: Inoue, Jin, et al.
Publicado: (2008)

Structural and biochemical characterization of an RNA/DNA binding motif in the N-terminal domain of RecQ4 helicases
por: Marino, Francesca, et al.
Publicado: (2016)

The RecQ DNA helicase Rqh1 constrains Exonuclease 1-dependent recombination at stalled replication forks
por: Osman, Fekret, et al.
Publicado: (2016)

Single molecule kinetics uncover roles for E. coli RecQ DNA helicase domains and interaction with SSB
por: Bagchi, Debjani, et al.
Publicado: (2018)

Inhibition of E. coli RecQ Helicase Activity by Structurally Distinct DNA Lesions: Structure—Function Relationships
por: Sales, Ana H., et al.
Publicado: (2022)

Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5
por: Newman, Joseph A., et al.
Publicado: (2017)

Human RECQ5β helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork
por: Kanagaraj, Radhakrishnan, et al.
Publicado: (2006)

Translocation of Saccharomyces cerevisiae Pif1 helicase monomers on single-stranded DNA
por: Galletto, Roberto, et al.
Publicado: (2013)

Single-molecule visualization of Pif1 helicase translocation on single-stranded DNA
por: Mustafi, Mainak, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_7tbddf4kp9jp0rasj3mn7ao4p2