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Exploring monovalent and multivalent peptides for the inhibition of FBP21-tWW
The coupling of peptides to polyglycerol carriers represents an important route towards the multivalent display of protein ligands. In particular, the inhibition of low affinity intracellular protein–protein interactions can be addressed by this design. We have applied this strategy to develop bindi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464085/ https://www.ncbi.nlm.nih.gov/pubmed/26124874 http://dx.doi.org/10.3762/bjoc.11.80 |