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Exploring monovalent and multivalent peptides for the inhibition of FBP21-tWW

The coupling of peptides to polyglycerol carriers represents an important route towards the multivalent display of protein ligands. In particular, the inhibition of low affinity intracellular protein–protein interactions can be addressed by this design. We have applied this strategy to develop bindi...

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Detalles Bibliográficos
Autores principales: Henning, Lisa Maria, Bhatia, Sumati, Bertazzon, Miriam, Marczynke, Michaela, Seitz, Oliver, Volkmer, Rudolf, Haag, Rainer, Freund, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464085/
https://www.ncbi.nlm.nih.gov/pubmed/26124874
http://dx.doi.org/10.3762/bjoc.11.80

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