Leptin modulates the expression of catabolic genes in rat nucleus pulposus cells through the mitogen-activated protein kinase and Janus kinase 2/signal transducer and activator of transcription 3 pathways

Obesity has been demonstrated to be involved in the progress of intervertebral disc degeneration (IDD). However, the associated mechanisms remain to be elucidated. The purpose the present study was to examine the effect of leptin on the expression of degeneration-associated genes in rat nucleus pulp...

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Detalles Bibliográficos
Autores principales: MIAO, DAOYI, ZHANG, LINGZHOU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464091/
https://www.ncbi.nlm.nih.gov/pubmed/25892402
http://dx.doi.org/10.3892/mmr.2015.3646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464091/
https://www.ncbi.nlm.nih.gov/pubmed/25892402
http://dx.doi.org/10.3892/mmr.2015.3646

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