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A unified framework for estimating parameters of kinetic biological models

BACKGROUND: Utilizing kinetic models of biological systems commonly require computational approaches to estimate parameters, posing a variety of challenges due to their highly non-linear and dynamic nature, which is further complicated by the issue of non-identifiability. We propose a novel paramete...

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Detalles Bibliográficos
Autores principales: Baker, Syed Murtuza, Poskar, C Hart, Schreiber, Falk, Junker, Björn H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464135/
https://www.ncbi.nlm.nih.gov/pubmed/25886743
http://dx.doi.org/10.1186/s12859-015-0500-9