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Single-molecule modeling of mRNA degradation by miRNA: Lessons from data
Recent experimental results on the effect of miRNA on the decay of its target mRNA have been analyzed against a previously hypothesized single molecule degradation pathway. According to that hypothesis, the silencing complex (miRISC) first interacts with its target mRNA and then recruits the protein...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464216/ https://www.ncbi.nlm.nih.gov/pubmed/26050661 http://dx.doi.org/10.1186/1752-0509-9-S3-S2 |