Human FMO2-based microbial whole-cell catalysts for drug metabolite synthesis

BACKGROUND: Getting access to authentic human drug metabolites is an important issue during the drug discovery and development process. Employing recombinant microorganisms as whole-cell biocatalysts constitutes an elegant alternative to organic synthesis to produce these compounds. The present work...

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Detalles Bibliográficos
Autores principales: Geier, Martina, Bachler, Thorsten, Hanlon, Steven P, Eggimann, Fabian K, Kittelmann, Matthias, Weber, Hansjörg, Lütz, Stephan, Wirz, Beat, Winkler, Margit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464233/
https://www.ncbi.nlm.nih.gov/pubmed/26062974
http://dx.doi.org/10.1186/s12934-015-0262-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464233/
https://www.ncbi.nlm.nih.gov/pubmed/26062974
http://dx.doi.org/10.1186/s12934-015-0262-0

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