VRK1 regulates Cajal body dynamics and protects coilin from proteasomal degradation in cell cycle

Cajal bodies (CBs) are nuclear organelles associated with ribonucleoprotein functions and RNA maturation. CBs are assembled on coilin, its main scaffold protein, in a cell cycle dependent manner. The Ser-Thr VRK1 (vaccinia-related kinase 1) kinase, whose activity is also cell cycle regulated, intera...

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Detalles Bibliográficos
Autores principales: Cantarero, Lara, Sanz-García, Marta, Vinograd-Byk, Hadar, Renbaum, Paul, Levy-Lahad, Ephrat, Lazo, Pedro A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464288/
https://www.ncbi.nlm.nih.gov/pubmed/26068304
http://dx.doi.org/10.1038/srep10543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464288/
https://www.ncbi.nlm.nih.gov/pubmed/26068304
http://dx.doi.org/10.1038/srep10543

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