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Host-virus interaction: the antiviral defense function of small interfering RNAs can be enhanced by host microRNA-7 in vitro

Small interfering RNAs (siRNAs) directed against poliovirus (PV) and other viruses effectively inhibit viral replication and have been developed as antiviral agents. Here, we demonstrate that a specific siRNA targeting the region between nucleotides 100–125 (siRNA-100) from the 5′-untranslated regio...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoying, Liu, Dongyun, Zhang, Sheng, Wei, Xiujuan, Song, Jie, Zhang, Yupei, Jin, Min, Shen, Zhiqiang, Wang, Xinwei, Feng, Zhichun, Li, Junwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464290/
https://www.ncbi.nlm.nih.gov/pubmed/26067353
http://dx.doi.org/10.1038/srep09722