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Peroxisome proliferator-activated receptor-γ agonist inhibits the mammalian target of rapamycin signaling pathway and has a protective effect in a rat model of status epilepticus

Peroxisome proliferator-activated receptor γ (PPAR-γ) has a protective role in several neurological diseases. The present study investigated the effect of the PPAR-γ agonist, pioglitazone, on the mammalian target of rapamycin (mTOR) signaling pathway in a rat model of pentylenetetrazol (PTZ)-induced...

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Detalles Bibliográficos
Autores principales: SAN, YONG-ZHI, LIU, YU, ZHANG, YU, SHI, PING-PING, ZHU, YU-LAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464309/
https://www.ncbi.nlm.nih.gov/pubmed/25891824
http://dx.doi.org/10.3892/mmr.2015.3641