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Biology of PXR: role in drug-hormone interactions

Hormonal homeostasis is essential for a variety of physiological and pathological processes. Elimination and detoxification of xenobiotics, such as drugs introduced into the human body, could disrupt the balance of hormones due to the induction of drug metabolizing enzymes (DMEs) and transporters. P...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Dai, Shu, Guo, Yan, Xie, Wen, Zhai, Yonggong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464432/
https://www.ncbi.nlm.nih.gov/pubmed/26417296