Cargando…

Synthesis of multivalent carbohydrate mimetics with aminopolyol end groups and their evaluation as L-selectin inhibitors

In this article a series of divalent and trivalent carbohydrate mimetics on the basis of an enantiopure aminopyran and of serinol is described. These aminopolyols are connected by amide bonds to carboxylic acid derived spacer units either by Schotten–Baumann acylation or by coupling employing HATU a...

Descripción completa

Detalles Bibliográficos
Autores principales: Salta, Joana, Dernedde, Jens, Reissig, Hans-Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464473/
https://www.ncbi.nlm.nih.gov/pubmed/26124866
http://dx.doi.org/10.3762/bjoc.11.72