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Molecular docking and simulation of Curcumin with Geranylgeranyl Transferase1 (GGTase1) and Farnesyl Transferase (FTase)

Protein prenylation is a posttranslational modification that is indispensable for translocation of membrane GTPases like Ras, Rho, Ras etc. Proteins of Ras family undergo farnesylation by FTase while Rho family goes through geranylgeranylation by GGTase1. There is only an infinitesimal difference in...

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Detalles Bibliográficos
Autores principales: Subramani, Parasuraman Aiya, Narala, Venkata Ramireddy, Michael, R Dinakaran, Lomada, Dakshayani, Reddy, Madhava C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464541/
https://www.ncbi.nlm.nih.gov/pubmed/26124569
http://dx.doi.org/10.6026/97320630011248