Use of in-silico assays to characterize the ADMET profile and identify potential therapeutic targets of fusarochromanone, a novel anti-cancer agent

PURPOSE: For 30 years nature has provided a plethora of natural products with potential meaningful anti-cancer activity. Fusarochromanone (FC101a) is a small molecule fungal metabolite exhibiting potent in-vitro growth inhibitory effects and is capable of inducing apoptosis, suppressing angiogenesis...

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Detalles Bibliográficos
Autores principales: El-Saadi, Madison Wynne, Williams-Hart, Tara, Salvatore, Brian A, Mahdavian, Elahe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464579/
https://www.ncbi.nlm.nih.gov/pubmed/26820891
http://dx.doi.org/10.1186/s40203-015-0010-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464579/
https://www.ncbi.nlm.nih.gov/pubmed/26820891
http://dx.doi.org/10.1186/s40203-015-0010-5

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