SIRT6 protein deacetylase interacts with MYH DNA glycosylase, APE1 endonuclease, and Rad9–Rad1–Hus1 checkpoint clamp

BACKGROUND: SIRT6, a member of the NAD(+)-dependent histone/protein deacetylase family, regulates genomic stability, metabolism, and lifespan. MYH glycosylase and APE1 are two base excision repair (BER) enzymes involved in mutation avoidance from oxidative DNA damage. Rad9–Rad1–Hus1 (9–1–1) checkpoi...

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Detalles Bibliográficos
Autores principales: Hwang, Bor-Jang, Jin, Jin, Gao, Ying, Shi, Guoli, Madabushi, Amrita, Yan, Austin, Guan, Xin, Zalzman, Michal, Nakajima, Satoshi, Lan, Li, Lu, A-Lien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464616/
https://www.ncbi.nlm.nih.gov/pubmed/26063178
http://dx.doi.org/10.1186/s12867-015-0041-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464616/
https://www.ncbi.nlm.nih.gov/pubmed/26063178
http://dx.doi.org/10.1186/s12867-015-0041-9

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