The chemokine receptor CCR6 facilitates the onset of mammary neoplasia in the MMTV-PyMT mouse model via recruitment of tumor-promoting macrophages

BACKGROUND: The expression of the chemokine receptor CCR6 has been previously correlated with higher grades and stages of breast cancer and decreased relapse-free survival. Also, its cognate chemokine ligand CCL20 has been reported to induce proliferation of cultured human breast epithelial cells. M...

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Detalles Bibliográficos
Autores principales: Boyle, Sarah T., Faulkner, Jessica W., McColl, Shaun R., Kochetkova, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464622/
https://www.ncbi.nlm.nih.gov/pubmed/26047945
http://dx.doi.org/10.1186/s12943-015-0394-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464622/
https://www.ncbi.nlm.nih.gov/pubmed/26047945
http://dx.doi.org/10.1186/s12943-015-0394-1

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