Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment

BACKGROUND: Interindividual epigenetic variation that occurs systemically must be established prior to gastrulation in the very early embryo and, because it is systemic, can be assessed in easily biopsiable tissues. We employ two independent genome-wide approaches to search for such variants. RESULT...

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Detalles Bibliográficos
Autores principales: Silver, Matt J, Kessler, Noah J, Hennig, Branwen J, Dominguez-Salas, Paula, Laritsky, Eleonora, Baker, Maria S, Coarfa, Cristian, Hernandez-Vargas, Hector, Castelino, Jovita M, Routledge, Michael N, Gong, Yun Yun, Herceg, Zdenko, Lee, Yong Sun, Lee, Kwanbok, Moore, Sophie E, Fulford, Anthony J, Prentice, Andrew M, Waterland, Robert A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464629/
https://www.ncbi.nlm.nih.gov/pubmed/26062908
http://dx.doi.org/10.1186/s13059-015-0660-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464629/
https://www.ncbi.nlm.nih.gov/pubmed/26062908
http://dx.doi.org/10.1186/s13059-015-0660-y

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