Reovirus FAST Proteins Drive Pore Formation and Syncytiogenesis Using a Novel Helix-Loop-Helix Fusion-Inducing Lipid Packing Sensor

Pore formation is the most energy-demanding step during virus-induced membrane fusion, where high curvature of the fusion pore rim increases the spacing between lipid headgroups, exposing the hydrophobic interior of the membrane to water. How protein fusogens breach this thermodynamic barrier to por...

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Detalles Bibliográficos
Autores principales: Read, Jolene, Clancy, Eileen K., Sarker, Muzaddid, de Antueno, Roberto, Langelaan, David N., Parmar, Hiren B., Shin, Kyungsoo, Rainey, Jan K., Duncan, Roy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464655/
https://www.ncbi.nlm.nih.gov/pubmed/26061049
http://dx.doi.org/10.1371/journal.ppat.1004962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464655/
https://www.ncbi.nlm.nih.gov/pubmed/26061049
http://dx.doi.org/10.1371/journal.ppat.1004962

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