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Development of a genetic tool for functional screening of anti-malarial bioactive extracts in metagenomic libraries

BACKGROUND: The chemical treatment of Plasmodium falciparum for human infections is losing efficacy each year due to the rise of resistance. One possible strategy to find novel anti-malarial drugs is to access the largest reservoir of genomic biodiversity source on earth present in metagenomes of en...

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Detalles Bibliográficos
Autores principales: Mongui, Alvaro, Pérez-Llanos, Francy J., Yamamoto, Marcio M., Lozano, Marcela, Zambrano, Maria M., Del Portillo, Patricia, Fernández-Becerra, Carmen, Restrepo, Silvia, Del Portillo, Hernando A., Junca, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464701/
https://www.ncbi.nlm.nih.gov/pubmed/26040274
http://dx.doi.org/10.1186/s12936-015-0748-6