High-level expression of a novel liver-targeting fusion interferon with preferred Escherichia coli codon preference and its anti-hepatitis B virus activity in vivo

BACKGROUND: In our previous study, a novel liver-targeting fusion interferon (IFN-CSP) combining IFN α2b with plasmodium region I peptide was successfully constructed. IFN-CSP has significant inhibition effects on HBV-DNA replication in HepG2.2.15 cells. The aim of the present investigation was focu...

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Detalles Bibliográficos
Autores principales: Lu, Xuemei, Wang, Jie, Jin, Xiaobao, Zhu, Jiayong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464711/
https://www.ncbi.nlm.nih.gov/pubmed/26063245
http://dx.doi.org/10.1186/s12896-015-0177-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464711/
https://www.ncbi.nlm.nih.gov/pubmed/26063245
http://dx.doi.org/10.1186/s12896-015-0177-1

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