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High-level expression of a novel liver-targeting fusion interferon with preferred Escherichia coli codon preference and its anti-hepatitis B virus activity in vivo

BACKGROUND: In our previous study, a novel liver-targeting fusion interferon (IFN-CSP) combining IFN α2b with plasmodium region I peptide was successfully constructed. IFN-CSP has significant inhibition effects on HBV-DNA replication in HepG2.2.15 cells. The aim of the present investigation was focu...

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Detalles Bibliográficos
Autores principales:	Lu, Xuemei, Wang, Jie, Jin, Xiaobao, Zhu, Jiayong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464711/ https://www.ncbi.nlm.nih.gov/pubmed/26063245 http://dx.doi.org/10.1186/s12896-015-0177-1

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