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From Boolean Network Model to Continuous Model Helps in Design of Functional Circuits

Computational circuit design with desired functions in a living cell is a challenging task in synthetic biology. To achieve this task, numerous methods that either focus on small scale networks or use evolutionary algorithms have been developed. Here, we propose a two-step approach to facilitate the...

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Detalles Bibliográficos
Autores principales: Shao, Bin, Liu, Xiang, Zhang, Dongliang, Wu, Jiayi, Ouyang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464762/
https://www.ncbi.nlm.nih.gov/pubmed/26061094
http://dx.doi.org/10.1371/journal.pone.0128630