Cargando…

Cardiospecific CD36 suppression by lentivirus-mediated RNA interference prevents cardiac hypertrophy and systolic dysfunction in high-fat-diet induced obese mice

BACKGROUND: Fatty acid (FA) catabolism abnormality has been proved to play an important role in obesity-related cardiomyopathy. We hypothesized that cardiospecific suppression of CD36, the predominant membrane FA transporter, would protect against obesity-related cardiomyopathy. METHODS: Four-wk-old...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yijie, Bao, Mingwei, Dai, Mingyan, Wang, Xin, He, Wenbo, Tan, Tuantuan, Lin, Dandan, Wang, Wei, Wen, Ying, Zhang, Rui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464858/ https://www.ncbi.nlm.nih.gov/pubmed/26036798 http://dx.doi.org/10.1186/s12933-015-0234-z

Ejemplares similares

X-Linked Dilated Cardiomyopathy: A Cardiospecific Phenotype of Dystrophinopathy
por: Nakamura, Akinori
Publicado: (2015)

Treatment of hypertrophic cardiomyopathy caused by cardiospecific variants of Fabry disease with chaperone therapy
por: Müntze, Jonas, et al.
Publicado: (2018)

Metabolic Pathway of Cardiospecific Troponins: From Fundamental Aspects to Diagnostic Role (Comprehensive Review)
por: Chaulin, Aleksey M.
Publicado: (2022)

The influence of lentivirus-mediated CXCR4 RNA interference on hepatic metastasis of colorectal cancer
por: WANG, TIAN-BAO, et al.
Publicado: (2014)

Hyperglycemia and nocturnal systolic blood pressure are associatedwith left ventricular hypertrophy and diastolic dysfunction in hypertensive diabetic patients
por: Felício, João S, et al.
Publicado: (2006)

Cardiospecific Overexpression of ATPGD1 (Carnosine Synthase) Increases Histidine Dipeptide Levels and Prevents Myocardial Ischemia Reperfusion Injury
por: Zhao, Jingjing, et al.
Publicado: (2020)

Modern View on the Role of Sex-Specific Levels of High-Sensitive Cardiospecific Troponins T and I in the Diagnosis of Myocardial Infarction
por: Chaulin, Aleksey
Publicado: (2023)

Targeting PPM1D by lentivirus-mediated RNA interference inhibits the tumorigenicity of bladder cancer cells
por: Wang, W., et al.
Publicado: (2014)

Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis
por: Chen, Jie, et al.
Publicado: (2012)

Lentivirus-mediated RNA interference of vascular endothelial growth factor in monkey eyes with iris neovascularization
por: Yuan, Meng-Ke, et al.
Publicado: (2010)

Inhibition of the Hypoxia-Inducible Factor 1α–Induced Cardiospecific HERNA1 Enhance-Templated RNA Protects From Heart Disease
por: Mirtschink, Peter, et al.
Publicado: (2019)

Hypertension as One of the Main Non-Myocardial Infarction-Related Causes of Increased Cardiospecific Troponins: From Mechanisms to Significance in Current Medical Practice
por: Chaulin, Aleksey Michailovich
Publicado: (2022)

Dickkopf-3 upregulation mediates the cardioprotective effects of curcumin on chronic heart failure
por: Cao, Quan, et al.
Publicado: (2018)

Contribution of serum FGF21 level to the identification of left ventricular systolic dysfunction and cardiac death
por: Shen, Yun, et al.
Publicado: (2017)

Mutations in IL36RN are associated with geographic tongue
por: Liang, Jianying, et al.
Publicado: (2016)

Clonal Interference in the Evolution of Influenza
por: Strelkowa, Natalja, et al.
Publicado: (2012)

Lentivirus‐mediated shRNA interference of ghrelin receptor blocks proliferation in the colorectal cancer cells
por: Liu, An, et al.
Publicado: (2016)

Targeting CRMP-4 by lentivirus-mediated RNA interference inhibits SW480 cell proliferation and colorectal cancer growth
por: Chen, Si-Le, et al.
Publicado: (2016)

Lentivirus‐mediated disintegrin and metalloproteinase 17 RNA interference reversed the acquired resistance to gefitinib in lung adenocarcinoma cells in vitro
por: Li, Ya‐Qing, et al.
Publicado: (2017)

Lentivirus-mediated RNA interference inhibits the tumorigenicity of cluster of differentiation 44(+) tumor cells in hypopharyngeal cancer
por: Shen, Chenling, et al.
Publicado: (2017)

Lentivirus-mediated RNA interference of clusterin enhances the chemosensitivity of EJ bladder cancer cells to epirubicin in vitro
por: Lu, Jian, et al.
Publicado: (2021)

Lentivirus-mediated RNA interference targeting EBNA1 gene inhibits the growth of GT-38 cells in vitro and in vivo
por: Wang, Jian, et al.
Publicado: (2019)

Effect of premature birth on long-term systolic blood pressure variability in women
por: Shi, Linying, et al.
Publicado: (2018)

Lower facial remodeling with botulinum toxin type A for the treatment of masseter hypertrophy
por: Klein, Fernanda Homem de Mello de Souza, et al.
Publicado: (2014)

RNA packaging in lentiviruses
por: Lever, Andrew ML
Publicado: (2009)

Escherichia coli Metabolite Profiling Leads to the Development of an RNA Interference Strain for Caenorhabditis elegans
por: Neve, Isaiah A. A., et al.
Publicado: (2019)

Distinguishing Driver and Passenger Mutations in an Evolutionary History Categorized by Interference
por: Illingworth, Christopher J. R., et al.
Publicado: (2011)

Lentivirus-mediated short hairpin RNA interference of CENPK inhibits growth of colorectal cancer cells with overexpression of Cullin 4A
por: Li, Xian, et al.
Publicado: (2022)

Modulating Crossover Frequency and Interference for Obligate Crossovers in Saccharomyces cerevisiae Meiosis
por: Chakraborty, Parijat, et al.
Publicado: (2017)

Association of Interarm Systolic Blood Pressure Difference with Atherosclerosis and Left Ventricular Hypertrophy
por: Su, Ho-Ming, et al.
Publicado: (2012)

Prognostic significance of right ventricular hypertrophy and systolic function in Anderson–Fabry disease
por: Graziani, Francesca, et al.
Publicado: (2020)

Lack of association between mutation in IL36RN and palmoplantar pustular psoriasis in Chinese patients()()
por: Xiaoling, Yu, et al.
Publicado: (2019)

Lentivirus-mediated short hairpin RNA interference targeting TNF-alpha in macrophages inhibits particle-induced inflammation and osteolysis in vitro and in vivo
por: Qin, Chu-qiang, et al.
Publicado: (2016)

Association Between Inferior Turbinate Hypertrophy and Extraesophageal Reflux
por: Zeleník, Karol, et al.
Publicado: (2022)

Tunable Transcriptional Interference at the Endogenous Alcohol Dehydrogenase Gene Locus in Drosophila melanogaster
por: Jorgensen, Victoria, et al.
Publicado: (2020)

Lentivirus-mediated shRNA interference of clusterin blocks proliferation, motility, invasion and cell cycle in the ovarian cancer cells
por: Fu, Yanxia, et al.
Publicado: (2015)

Diastolic blood pressure achieved at target systolic blood pressure (120–140 mm Hg) and dabigatran-related bleeding in patients with nonvalvular atrial fibrillation: A real-world study
por: Yu, Yu, et al.
Publicado: (2020)

Lentivirus Gene Engineering Protocols
por: Takeuchi, Y
Publicado: (2004)

Clinical features of subclinical left ventricular systolic dysfunction in patients with diabetes mellitus
por: Mochizuki, Yasuhide, et al.
Publicado: (2015)

Post-systolic shortening index by echocardiography evaluation of dyssynchrony in the non-dilated and hypertrophied left ventricle
por: Saijo, Yoshihito, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4vugekb8desk9pvig352via39b