Cargando…
Cardiospecific CD36 suppression by lentivirus-mediated RNA interference prevents cardiac hypertrophy and systolic dysfunction in high-fat-diet induced obese mice
BACKGROUND: Fatty acid (FA) catabolism abnormality has been proved to play an important role in obesity-related cardiomyopathy. We hypothesized that cardiospecific suppression of CD36, the predominant membrane FA transporter, would protect against obesity-related cardiomyopathy. METHODS: Four-wk-old...
Autores principales: | Zhang, Yijie, Bao, Mingwei, Dai, Mingyan, Wang, Xin, He, Wenbo, Tan, Tuantuan, Lin, Dandan, Wang, Wei, Wen, Ying, Zhang, Rui |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4464858/ https://www.ncbi.nlm.nih.gov/pubmed/26036798 http://dx.doi.org/10.1186/s12933-015-0234-z |
Ejemplares similares
-
X-Linked Dilated Cardiomyopathy: A Cardiospecific Phenotype of Dystrophinopathy
por: Nakamura, Akinori
Publicado: (2015) -
Treatment of hypertrophic cardiomyopathy caused by cardiospecific variants of Fabry disease with chaperone therapy
por: Müntze, Jonas, et al.
Publicado: (2018) -
Metabolic Pathway of Cardiospecific Troponins: From Fundamental Aspects to Diagnostic Role (Comprehensive Review)
por: Chaulin, Aleksey M.
Publicado: (2022) -
The influence of lentivirus-mediated CXCR4 RNA interference on hepatic metastasis of colorectal cancer
por: WANG, TIAN-BAO, et al.
Publicado: (2014) -
Hyperglycemia and nocturnal systolic blood pressure are associatedwith left ventricular hypertrophy and diastolic dysfunction in hypertensive diabetic patients
por: Felício, João S, et al.
Publicado: (2006)