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AllelicImbalance: an R/ bioconductor package for detecting, managing, and visualizing allele expression imbalance data from RNA sequencing

BACKGROUND: One aspect in which RNA sequencing is more valuable than microarray-based methods is the ability to examine the allelic imbalance of the expression of a gene. This process is often a complex task that entails quality control, alignment, and the counting of reads over heterozygous single-...

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Detalles Bibliográficos
Autores principales: Gådin, Jesper R., van’t Hooft, Ferdinand M., Eriksson, Per, Folkersen, Lasse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465016/
https://www.ncbi.nlm.nih.gov/pubmed/26066318
http://dx.doi.org/10.1186/s12859-015-0620-2