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Quantitative high resolution melting: two methods to determine SNP allele frequencies from pooled samples

BACKGROUND: The advent of next-generation sequencing has brought about an explosion of single nucleotide polymorphism (SNP) data in non-model organisms; however, profiling these SNPs across multiple natural populations still requires substantial time and resources. RESULTS: Here, we introduce two co...

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Detalles Bibliográficos
Autores principales: Capper, Roxana L., Jin, Young K., Lundgren, Petra B., Peplow, Lesa M., Matz, Mikhail V., van Oppen, Madeleine J. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465018/
https://www.ncbi.nlm.nih.gov/pubmed/26070466
http://dx.doi.org/10.1186/s12863-015-0222-z