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CD8(+) T Cells Specific to Apoptosis-Associated Antigens Predict the Response to Tumor Necrosis Factor Inhibitor Therapy in Rheumatoid Arthritis

CD8(+) T cells specific to caspase-cleaved antigens derived from apoptotic T cells (apoptotic epitopes) represent a principal player in chronic immune activation, which is known to amplify immunopathology in various inflammatory diseases. The purpose of the present study was to investigate the relat...

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Detalles Bibliográficos
Autores principales: Citro, Alessandra, Scrivo, Rossana, Martini, Helene, Martire, Carmela, De Marzio, Paolo, Vestri, Anna Rita, Sidney, John, Sette, Alessandro, Barnaba, Vincenzo, Valesini, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465029/
https://www.ncbi.nlm.nih.gov/pubmed/26061065
http://dx.doi.org/10.1371/journal.pone.0128607