Necroptosis Interfaces with MOMP and the MPTP in Mediating Cell Death

During apoptosis the pro-death Bcl-2 family members Bax and Bak induce mitochondrial outer membrane permeabilization (MOMP) to mediate cell death. Recently, it was shown that Bax and Bak are also required for mitochondrial permeability transition pore (MPTP)-dependent necrosis, where, in their non-o...

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Detalles Bibliográficos
Autores principales: Karch, Jason, Kanisicak, Onur, Brody, Matthew J., Sargent, Michelle A., Michael, Demetria M., Molkentin, Jeffery D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465034/
https://www.ncbi.nlm.nih.gov/pubmed/26061004
http://dx.doi.org/10.1371/journal.pone.0130520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465034/
https://www.ncbi.nlm.nih.gov/pubmed/26061004
http://dx.doi.org/10.1371/journal.pone.0130520

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