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Necroptosis Interfaces with MOMP and the MPTP in Mediating Cell Death
During apoptosis the pro-death Bcl-2 family members Bax and Bak induce mitochondrial outer membrane permeabilization (MOMP) to mediate cell death. Recently, it was shown that Bax and Bak are also required for mitochondrial permeability transition pore (MPTP)-dependent necrosis, where, in their non-o...
Autores principales: | Karch, Jason, Kanisicak, Onur, Brody, Matthew J., Sargent, Michelle A., Michael, Demetria M., Molkentin, Jeffery D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465034/ https://www.ncbi.nlm.nih.gov/pubmed/26061004 http://dx.doi.org/10.1371/journal.pone.0130520 |
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