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New tricks for p53 regulation – restraint by protein coding RNAs
P53 is most well-known for its tumor suppressive function in differentiated cells. Its activities in embryonic stem cells (ESCs) are, however, less well understood. For many years it was thought that p53 is not active at all in ESCs and unable to elicit a DNA damage response in this cell type. In th...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465304/ https://www.ncbi.nlm.nih.gov/pubmed/26075053 http://dx.doi.org/10.1186/s13578-015-0022-1 |