Prevalence of mutations in a panel of breast cancer susceptibility genes in BRCA1/2 negative patients with early onset breast cancer

PURPOSE: Clinical testing for germline variation in multiple cancer susceptibility genes is available using massively parallel sequencing. Limited information is available for pre-test genetic counseling regarding the spectrum of mutations and variants of uncertain significance (VUSs) in defined pat...

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Detalles Bibliográficos
Autores principales: Maxwell, Kara N., Wubbenhorst, Bradley, D’Andrea, Kurt, Garman, Bradley, Long, Jessica M., Powers, Jacquelyn, Rathbun, Katherine, Stopfer, Jill E., Zhu, Jiajun, Bradbury, Angela R., Simon, Michael S., DeMichele, Angela, Domchek, Susan M., Nathanson, Katherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465412/
https://www.ncbi.nlm.nih.gov/pubmed/25503501
http://dx.doi.org/10.1038/gim.2014.176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465412/
https://www.ncbi.nlm.nih.gov/pubmed/25503501
http://dx.doi.org/10.1038/gim.2014.176

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