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Efficacy of autologous stem cell-based therapy for osteonecrosis of the femoral head in sickle cell disease: a five-year follow-up study

INTRODUCTION: Stem cell therapy with bone marrow-derived mononuclear cells (BMMCs) is an option for improving joint function in osteonecrosis of the femoral head (ONFH). Bone marrow-derived mesenchymal stromal cell (MSC) numbers and their osteogenic differentiation are decreased in patients with ONF...

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Detalles Bibliográficos
Autores principales: Daltro, Gildasio Cerqueira, Fortuna, Vitor, de Souza, Eliane Silva, Salles, Marcela Miranda, Carreira, Ana Claudia, Meyer, Roberto, Freire, Songeli Menezes, Borojevic, Radovan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465459/
https://www.ncbi.nlm.nih.gov/pubmed/26021713
http://dx.doi.org/10.1186/s13287-015-0105-2