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Heterogeneous Pathways and Timing of Factor Departure during Translation Initiation

Initiation of translation establishes the reading frame for protein synthesis and is a key point of regulation(1). Initiation involves factor-driven assembly at a start codon of an mRNA of an elongation competent 70S ribosomal particle (in bacteria) from separated 30S and 50S subunits and initiator...

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Detalles Bibliográficos
Autores principales: Tsai, Albert, Petrov, Alexey, Marshall, R. Andrew, Korlach, Jonas, Uemura, Sotaro, Puglisi, Joseph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465488/
https://www.ncbi.nlm.nih.gov/pubmed/22722848
http://dx.doi.org/10.1038/nature11172