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Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1

Parkinson's disease (PD) is a pervasive, aging-related neurodegenerative disease whose cardinal motor symptoms reflect the loss of a small group of neurons – dopaminergic neurons in the substantia nigra pars compacta (SNc)(1). Mitochondrial oxidant stress is widely viewed as responsible for thi...

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Detalles Bibliográficos
Autores principales: Guzman, Jaime N., Sanchez-Padilla, Javier, Wokosin, David, Kondapalli, Jyothisri, Ilijic, Ema, Schumacker, Paul T., Surmeier, D. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465557/
https://www.ncbi.nlm.nih.gov/pubmed/21068725
http://dx.doi.org/10.1038/nature09536