Multi-Leu PACE4 Inhibitor Retention within Cells Is PACE4 Dependent and a Prerequisite for Antiproliferative Activity

The overexpression as well as the critical implication of the proprotein convertase PACE4 in prostate cancer progression has been previously reported and supported the development of peptide inhibitors. The multi-Leu peptide, a PACE4-specific inhibitor, was further generated and its capability to be...

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Detalles Bibliográficos
Autores principales: Couture, Frédéric, Ly, Kévin, Levesque, Christine, Kwiatkowska, Anna, Ait-Mohand, Samia, Desjardins, Roxane, Guérin, Brigitte, Day, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465654/
https://www.ncbi.nlm.nih.gov/pubmed/26114115
http://dx.doi.org/10.1155/2015/824014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465654/
https://www.ncbi.nlm.nih.gov/pubmed/26114115
http://dx.doi.org/10.1155/2015/824014

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