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Impaired Cellular Immunity in the Murine Neural Crest Conditional Deletion of Endothelin Receptor-B Model of Hirschsprung’s Disease

Hirschsprung’s disease (HSCR) is characterized by aganglionosis from failure of neural crest cell (NCC) migration to the distal hindgut. Up to 40% of HSCR patients suffer Hirschsprung’s-associated enterocolitis (HAEC), with an incidence that is unchanged from the pre-operative to the post-operative...

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Detalles Bibliográficos
Autores principales: Gosain, Ankush, Barlow-Anacker, Amanda J., Erickson, Chris S., Pierre, Joseph F., Heneghan, Aaron F., Epstein, Miles L., Kudsk, Kenneth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465674/
https://www.ncbi.nlm.nih.gov/pubmed/26061883
http://dx.doi.org/10.1371/journal.pone.0128822