Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway

Atherosclerotic lesions are accelerated in patients with diabetes. M1 (classically activated in contrast to M2 alternatively activated) macrophages play key roles in the progression of atherosclerosis. Since advanced glycation end products (AGEs) are major pathogenic factors and active inflammation...

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Detalles Bibliográficos
Autores principales: Jin, Xian, Yao, Tongqing, Zhou, Zhong'e, Zhu, Jian, Zhang, Song, Hu, Wei, Shen, Chengxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465680/
https://www.ncbi.nlm.nih.gov/pubmed/26114112
http://dx.doi.org/10.1155/2015/732450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465680/
https://www.ncbi.nlm.nih.gov/pubmed/26114112
http://dx.doi.org/10.1155/2015/732450

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