Cargando…
Cohesin-dependent globules and heterochromatin shape 3D genome architecture in S. pombe
Eukaryotic genomes are folded into three-dimensional structures, such as self-associating topological domains, the borders of which are enriched in cohesin and CCCTC-binding factor (CTCF) required for long-range interactions(1-7). How local chromatin interactions govern higher-order folding of chrom...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465753/ https://www.ncbi.nlm.nih.gov/pubmed/25307058 http://dx.doi.org/10.1038/nature13833 |