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Protective Effect of HLA-B*5701 and HLA-C -35 Genetic Variants in HIV-Positive Caucasians from Northern Poland

AIM OF THE STUDY: Association of two HLA class I variants with HIV-1 pretreatment viremia, CD4+ T cell count at the care-entry and CD4+ T cell nadir. METHODS: 414 HIV-positive Caucasians (30% women) aged 19-73 years were genotyped for HLA-C -35 (rs9264942) and HLA-B*5701 variants. HIV-1 viral load,...

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Detalles Bibliográficos
Autores principales: Leszczyszyn-Pynka, Magdalena, Aksak-Wąs, Bogusz, Urbańska, Anna, Parczewski, Miłosz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465896/
https://www.ncbi.nlm.nih.gov/pubmed/26068923
http://dx.doi.org/10.1371/journal.pone.0127867