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In Situ Peptide-MHC-II Tetramer Staining of Antigen-Specific CD4(+) T Cells in Tissues
The invention of peptide-MHC-tetramer technology to label antigen-specific T cells has led to an enhanced understanding of T lymphocyte biology. Here we describe the development of an in situ pMHC-II tetramer staining method to visualize antigen-specific CD4(+) T cells in tissues. This method comple...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465905/ https://www.ncbi.nlm.nih.gov/pubmed/26067103 http://dx.doi.org/10.1371/journal.pone.0128862 |