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Apolipoprotein E3 Inhibits Rho to Regulate the Mechanosensitive Expression of Cox2

Apolipoprotein E3 (apoE3) is thought to protect against atherosclerosis by enhancing reverse cholesterol transport. However, apoE3 also has cholesterol-independent effects that contribute to its anti-atherogenic properties. These include altering extracellular matrix protein synthesis and inhibiting...

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Detalles Bibliográficos
Autores principales: Hsu, Bernadette Y., Bae, Yong Ho, Mui, Keeley L., Liu, Shu-Lin, Assoian, Richard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465925/
https://www.ncbi.nlm.nih.gov/pubmed/26068461
http://dx.doi.org/10.1371/journal.pone.0128974