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Identification of Influenza A/PR/8/34 Donor Viruses Imparting High Hemagglutinin Yields to Candidate Vaccine Viruses in Eggs

One of the important lessons learned from the 2009 H1N1 pandemic is that a high yield influenza vaccine virus is essential for efficient and timely production of pandemic vaccines in eggs. The current seasonal and pre-pandemic vaccine viruses are generated either by classical reassortment or reverse...

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Detalles Bibliográficos
Autores principales: Johnson, Adam, Chen, Li-Mei, Winne, Emily, Santana, Wanda, Metcalfe, Maureen G., Mateu-Petit, Guaniri, Ridenour, Callie, Hossain, M. Jaber, Villanueva, Julie, Zaki, Sherif R., Williams, Tracie L., Cox, Nancy J., Barr, John R., Donis, Ruben O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465931/
https://www.ncbi.nlm.nih.gov/pubmed/26068666
http://dx.doi.org/10.1371/journal.pone.0128982