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Caffeine does not entrain the circadian clock but improves daytime alertness in blind patients with non-24-hour rhythms
OBJECTIVE/BACKGROUND: Totally blind individuals are highly likely to suffer from Non-24-Hour Sleep-Wake Disorder due to a failure of light to reset the circadian pacemaker in the suprachiasmatic nuclei. In this outpatient case series, we investigated whether daily caffeine administration could entra...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465963/ https://www.ncbi.nlm.nih.gov/pubmed/25891543 http://dx.doi.org/10.1016/j.sleep.2015.01.018 |