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Caffeine does not entrain the circadian clock but improves daytime alertness in blind patients with non-24-hour rhythms

OBJECTIVE/BACKGROUND: Totally blind individuals are highly likely to suffer from Non-24-Hour Sleep-Wake Disorder due to a failure of light to reset the circadian pacemaker in the suprachiasmatic nuclei. In this outpatient case series, we investigated whether daily caffeine administration could entra...

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Detalles Bibliográficos
Autores principales: St. Hilaire, Melissa A., Lockley, Steven W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465963/
https://www.ncbi.nlm.nih.gov/pubmed/25891543
http://dx.doi.org/10.1016/j.sleep.2015.01.018