TNFα Amplifies DNaseI Expression in Renal Tubular Cells while IL-1β Promotes Nuclear DNaseI Translocation in an Endonuclease-Inactive Form

We have demonstrated that the renal endonuclease DNaseI is up-regulated in mesangial nephritis while down-regulated during progression of the disease. To determine the basis for these reciprocal DNaseI expression profiles we analyse processes accounting for an early increase in renal DNaseI expressi...

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Detalles Bibliográficos
Autores principales: Thiyagarajan, Dhivya, Rekvig, Ole Petter, Seredkina, Natalya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465975/
https://www.ncbi.nlm.nih.gov/pubmed/26065428
http://dx.doi.org/10.1371/journal.pone.0129485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465975/
https://www.ncbi.nlm.nih.gov/pubmed/26065428
http://dx.doi.org/10.1371/journal.pone.0129485

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