Heat Shock Protein 70 Prevents Hyperoxia-Induced Disruption of Lung Endothelial Barrier via Caspase-Dependent and AIF-Dependent Pathways

Exposure of pulmonary artery endothelial cells (PAECs) to hyperoxia results in a compromise in endothelial monolayer integrity, an increase in caspase-3 activity, and nuclear translocation of apoptosis-inducing factor (AIF), a marker of caspase-independent apoptosis. In an endeavor to identify prote...

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Detalles Bibliográficos
Autores principales: Kondrikov, Dmitry, Fulton, David, Dong, Zheng, Su, Yunchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465980/
https://www.ncbi.nlm.nih.gov/pubmed/26066050
http://dx.doi.org/10.1371/journal.pone.0129343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465980/
https://www.ncbi.nlm.nih.gov/pubmed/26066050
http://dx.doi.org/10.1371/journal.pone.0129343

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